20. Gbawe, Greater Accra (80,991):

Gbawe is a town in the Greater Accra Region of southeastern Ghana near the capital, Accra. Gbawe is the twentieth largest settlement in Ghana, in terms of population, with a population of 80,991 people.

19. Tema New Town, Greater Accra (83,267):

It is the 19th most populated city in Ghana.

18. Dome, Greater Accra (84,904):

Dome is a town in the Ga East Municipal district, a district in the Greater Accra Region of Ghana. Dome is the eighteenth largest settlement in Ghana, in terms of population, with a population of 84,904 people.

17. Lashibi, Greater Accra (86,188):

Lashibi is a town in the Greater Accra Region of southeastern Ghana near the capital Accra. Lashibi is the seventeenth most populous city in Ghana, with a population of 86,188 people.

16. Nungua, Greater Accra (86,431):

Nungua is a town in Ledzokuku-Krowor Municipal district in the Greater Accra Region of southeastern Ghana near the coast. Nungua is the sixteenth most populous settlement in Ghana, with a population of 86,431 people.

15. Ho, Volta Region (99,375):

Ho is a town and the capital of Ho Municipal District and the Volta Region of Ghana. Ho lies between Mount Adaklu and Mount Galenukui (Togo Atakora Range), and is home to a museum, a cathedral and a large prison. Ho has a settlement population of 99,375 people.

14. Techiman, Brong-Ahafo (104,212):

Techiman is a town and is the capital of Techiman Municipal of the Brong Ahafo Region of Ghana. Techiman is a leading market town in South Ghana. Techiman is together with Sunyani, one of the two major cities and settlements of Brong Ahafo region. Techiman has a settlement population of 104,212 people in 2013. It is located at a historical crossroads of trade routes and the Tano River, and serves as capital of the Techiman Municipal district.

13. Wa, Upper West (105,821):

Wa is a town and is the capital of Wa Municipal District and the Upper West Region of north Ghana. Wa has a settlement population of 105,821. Features of the town include several mosques, the Wa-Na Palace, a museum and a nearby hippopotamus sanctuary. The geography of Wa is notable for the dramatic monadnock Ombo Mountain which is located around Kaleo and visible from much of the Wa township.

12. Koforidua, Eastern region (130,810):

Koforidua, also popularly known as K-dua, is a city and capital of Eastern Region in south Ghana. Koforidua has a settlement population of 130,810 people.

11. Madina, Greater Accra (143,356):

Madina is a town in the Ga East Municipal district, a district in the Greater Accra Region of southeastern Ghana. Madina is next to the University of Ghana and houses the Institute of Local Government. It is the eleventh most populous settlement in Ghana, in terms of population, with a population of 143,356 people.

10. Tema, Greater Accra (161,612):

Tema is a city on the Gulf of Guinea and Atlantic coast of Ghana. It is located 25 kilometres (16 m), east of the capital city; Accra, in the region of Greater Accra, and is the capital of the Tema Metropolitan District. Tema is the tenth most populous settlement in Ghana, with a population of approximately 161,612 people – a marked decrease from its 2005 figure of 209,000. Tema is locally nicknamed the “Harbour Town” because of its status as Ghana’s largest seaport. See also: 10 Best Places to Visit in Accra 

9. Teshie, Greater Accra (176,597):

Teshie is a coastal town in the Ledzokuku-Krowor Municipal district, a district in the Greater Accra Region of south eastern Ghana. Teshie is the ninth most populous settlement in Ghana, in terms of population, with a population of 176,597 people.

8. Obuasi, Ashanti (180,334):

Obuasi is a town in southern part of the Ashanti Region, Ghana. Obuasi is the capital of the Obuasi Municipal which lies south of the regional capital city, Kumasi. Obuasi has a settlement population of 180,334 people. The mining community gives Obuasi its delicate mosaic of cultures from all over the county, the continent, and the rest of the world and hence its cosmopolitan culture. Wearing a ring of hills as its adornment, it sits quietly albeit industriously on the soil that births the single richest bullion gold bar on earth.

7. Cape Coast, Central Region (227,269):

Cape Coast, or Cabo Corso, is a city and fishing port, and the capital of Cape Coast Metropolitan District and Central Region of south Ghana. Cape Coast is situated on its south to the Gulf of Guinea.

6. Sunyani, Brong-Ahafo (248,496):

Sunyani is a city and the capital town of the Brong-Ahafo Region and the Sunyani Municipal of Ghana. Sunyani had a population of 248,496 at the 2012 census. See also: 28 Incredible Photos of Accra You’ll Mistake for London

5. Ashaiman, Greater Accra (298,841):

Ashaiman is a large town in Greater Accra Region of South Ghana and is the capital of Ashaiman Municipal district, a district in Greater Accra Region. Ashaiman has a not well known number of settlement population being estimated between some hundred thousands up to over one million people inhabitants according to World Gazetter.

4. Sekondi-Takoradi, Western Region (445,205):

Sekondi-Takoradi, a city comprising the twin cities of Sekondi and Takoradi, is the capital of Sekondi Takoradi Metropolitan District and the Western Region of Ghana. Sekondi-Takoradi is the region’s largest city and an industrial and commercial center, with a population of 445,205 people.

3. Tamale, Northern Region (562,919):

Tamale, officially called Tamale Metropolitan District is the capital town of the Northern Region of Ghana. Tamale is Ghana’s third city and the second largest by area size. It has a 2013 projected population of 562,919 according to the 2012 census, making it the third largest settlement in Ghana and the fastest growing city in West Africa.

2. Kumasi, Ashanti (2,069,350):

Kumasi (historically spelled Comassie or Coomassie), is a city in Ashanti Region, South Ghana and is among the largest metropolitan areas of Ghana. Kumasi is located near Lake Bosumtwi, in a Rain Forest region, and is the commercial, industrial and cultural capital of Asanteman. It is approximately 300 miles (480 km) north of the Equator and 100 miles (160 km) north of the Gulf of Guinea. Kumasi is alternatively known as “The Garden City” because of its many beautiful species of flowers and plants. It is also called Oseikrom.

1. Accra, Greater Accra (2,291,352):

The Greater Accra Region is the smallest of Ghana’s 10 administrative regions in terms of area, occupying a total land surface of 3,245 square kilometres or 1.4 per cent of the total land area of Ghana. In terms of population, however, it is the most populated region, with a population of 2,291,352.

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